[D-Trp7,9,10]-Substance P ( )

Catalog No. M30809 CAS No. 89430-38-6

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Product Name

[D-Trp7,9,10]-Substance P
Note

Research use only, not for human use.
Brief Description

Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Description

Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Synonyms
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

CAS Number

89430-38-6
Formula Weight

1588.9
Molecular Formula

C79H105N21O13S
Purity

>98% (HPLC)
Solubility

water:1 mg/mL
SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O
Chemical Name

1. Mukai et al (1992) G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 267 16237 PMID:

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